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ALNY ALNYLAM PHARMACEUTICALS, INC.

Trailing twelve months to 2025-12-31 · as filed 2026-02-12, not restated
Healthcare

Scale

Market cap
$31.3bn
Revenue TTM
$3.7bn
Net income TTM
$314m
Free cash flow
$465m
Composite score
60.2
Sector rank
#325

Valuation

P / E
99.8
EV / EBITDA
51.0
EV / sales
7.6
FCF yield
1.49%
Earnings yield vs 10-yr
-3.73pp

Earnings yield vs 10-yr compares what the business earns per pound invested against the 4.73% a 10-year US Treasury note pays for no equity risk. Negative means you are paying up front for growth not yet delivered.

Quality and growth

Net margin
8.4%
EBITDA margin
15.0%
ROE
39.8%
ROIC
Revenue growth
65.2%

Insider activity, last 90 days

Net open-market
$-1.15m
Buyers
0
Sellers
1

Open-market purchases and sales only. Grants, option exercises, gifts and shares withheld for tax are excluded: they are how people are paid, not what they think.

What management said

These goals include expanding to 10 tissue types and more than 40 clinical programs, delivering at least two new transformative medicines beyond TTR with blockbuster potential, investing approximately 30% of our revenues in non-GAAP R&D (including select external innovation), achieving 25%+ total revenue compound annual growth rate, and delivering approximately 30% non-GAAP operating margin through year-end 2030. Under our license agreement with Sanofi, Sanofi is eligible to receive tiered royalties on global annual net sales of AMVUTTRA across all indications in the following tiers: 15% of global annual net sales of $0 to $150.0 million; 17.5% of global annual net sales greater than $150.0 …ALNYLAM PHARMACEUTICALS, INC., 10-Q, period ended 2026-06-30, filed 2026-07-30

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